PCDHA12 Antikörper (N-Term)

Produktnummer ABIN2783721

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch PCDHA12 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für PCDHA12 Antikörper (N-Term) (ABIN2783721)

Target: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHA12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PCDHA12 Antikörper

Bindungsspezifität: N-Term

Sequenz: EVIVDRPLQV FHVDVEVKDI NDNPPVFRER EQKVPVSESA PLDSHFPLEG

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 83%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PCDHA12. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHA12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 941 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PCDHA12

Target: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Andere Bezeichnung: PCDHA12

Hintergrund: PCDHA12 is a potential calcium-dependent cell-adhesion protein. PCDHA12 may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: MGC138485, MGC141932, PCDH-ALPHA12
Protein Size: 941

Molekulargewicht: 99 kDa

Gen-ID: 56137

NCBI Accession: NM_018903, NP_061726

UniProt: Q9UN75